Gene description for PLEC
Gene name	plectin
Gene symbol	PLEC
Other names/aliases	EBS1 EBS5A EBS5B EBS5C EBS5D EBSMD EBSND EBSO EBSOG EBSPA HD1 LGMD2Q LGMDR17 PCN PLEC1 PLEC1b PLTN
Species	Homo sapiens
Experiment description of studies that identified PLEC in Neuroblastoma cells
1 Experiment ID 903 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25053844    Organism Homo sapiens Experiment description Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons Authors Goldie BJ, Dun MD, Lin M, Smith ND, Verrills NM, Dayas CV, Cairns MJ. Journal name Nucleic Acids Res Publication year 2014 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140076: EV-METRIC:38%
2 Experiment ID 1153 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22057275    Organism Homo sapiens Experiment description Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Authors Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, Hall GF. Journal name J Biol Chem Publication year 2012 Sample Neuroblastoma cells Sample name M1C cells (inducibly expressing wild-type human tau Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120107: EV-METRIC:11%, 11%